Selenium is one of the major trace elements required for redox functions and has significant roles in viral infections. oxidative stress is a characteristic feature of COVID-19 disease, which is linked with the immunopathological disorder observed in individuals with severe COVID-19. Selenium plays a key role in strengthening immunity, reducing oxidative stress, preventing viral infections and supporting critical illness.
Results: Selenium deficiency is related to oxidative stress and hyperinflammation seen in critical illness, and selenium deficiency is found to be associated with the severity of COVID-19 disease. Selenium supplementation at an appropriate dose may act as supportive therapy in COVID-19.
Reference
S. Khatiwada, A. Subedi, Curr Nutr Rep, 2021, 10, 125-136. A Mechanistic Link Between Selenium and Coronavirus Disease 2019 (COVID-19).
