Population studied: Six cohort studies, one case-control study and five cross-sectional studies were included.
Dosage & Duration: Ranging from 161mg/day average to 454mg/day average across studies, with follow up between 2.8 – 7.6 years.
Method: Bone health outcomes among adults aged >60 years, including bone mineral density (BMD), bone mineral content (BMC), bone turnover markers, and fracture risk in older adults.
Results: Qualitative evaluation demonstrated a positive trend between higher magnesium intake and higher hip and femoral neck BMD. Meta-analysis of four studies showed a significant positive association between magnesium intake and hip BMD. Orchard et al. found that total body BMD was 2% higher (p < 0.001), in women who consumed >422.5 mg/day compared with <206.5 mg/day. Ryder et al. found that, in white men and women, the total body BMD increased approximately 2% for every 100 mg/day increase in magnesium intake.
Reference
I. Groenendijl, M. V. Delft, P. Versloot, L. J. C. van Loon, L. C. P. G. M. de Groot, Bone, 2022, 154, 116233. Impact of magnesium on bone health in older adults: A systematic review and meta-analysis.
