Results: Observations from the Framingham Heart Study suggest that ≥180 mg dietary DHA/day, or ≈2.7 fish servings per week, is associated with an ≈50% reduction in dementia risk. This amount of DHA is generally found in one commercially available fish oil capsule.
The Blue Mountains Eye Study was a population-based survey of vision, common eye diseases, and diet in an urban population of 3654 persons aged ≥49 y. In the 2915 subjects evaluated for fish intake, 240 cases of early ARM and 72 cases of late ARM were identified. In this study, more frequent consumption of fish appeared to protect against late ARM after adjustment for age, sex, and smoking. The protective effect of fish intake commenced at a relatively low frequency of consumption (1–3 times/mo compared with intake <1 time per month; OR: 0.23; 95% CI: 0.08, 0.63).
Reference
E. J. Johnson, E. J. Schaefer. Am J Clin Nutr, 2006, 86, 1494S-1498S. Potential role of dietary n−3 fatty acids in the prevention of dementia and macular degeneration.
