Selenium to seleniumproteins – the role in COVID-19 – Tomo et al. 2021

Reactive oxygen species caused by oxidative stress during viral infection from rhinoviruses is followed by an activation of inflammatory pathways that lead to an increase in tissue destruction through the NF-κB pathway. Selenium is known to inhibit the activation of the NF-κB pathway thus reducing inflammation.

Selenium plays a major role in decreasing the ROS produced in response to various viral infections. Selenoprotein enzymes are essential in combating oxidative stress caused due to excessive generation of ROS. Selenium also has a role in inhibiting the activation of NF-κB, thus alleviating inflammation.

Results: There is unequivocal proof of the involvement of selenium with antioxidant mechanisms in the body, trials of selenium in the treatment of COVID-19 will offer newer opportunities for the treatment of COVID-19.

Reference

S. Tomo, G. Saikiran, M. Banerjee, S. Paul, EXCELI J, 2021, 20, 781-791. Selenium to seleniumproteins – the role in COVID-19.

Selenium to seleniumproteins – the role in COVID-19 – Tomo et al. 2021

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