The role of Evening Primrose Oil and skin health was first explored by Efamol’s founder David Horrobin over 40 years ago. Since then, we have conducted many scientific trials – many of them double blind placebo controlled into it’s effectiveness. There have been at least 22 clinical studies using EPO to treat atopic ezcema. A 1989 meta-analysis of 10 studies reported an overall improvement of 22% with a 25% improvement in the most uncomfortable symptom, which is itch. In 2006 a meta-analysis of 26 clinical studies including over 1200 patients confirmed its effectiveness for atopic eczema, showing it simultaneously improved itch, crusting, swelling and redness within 4 and 8 weeks after treatment is initiated. In 2009, topically applied Efamol Evening Primroise Oil was found to work as well as the leading brand of treatment for diaper or nappy rash.