Vitamins and Minerals for Energy, Fatigue and Cognition – Tardy et al. 2020

There is a strong biological and physiological rationale that indicates that the long-known involvement of vitamins and minerals in cellular energy production translates into functional and physiological outcomes in humans, including perceived physical and mental fatigue as well as psychological and cognitive functions.

Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia – Pouteau et al. 2018

Animal and clinical studies suggest complementary effects of magnesium and high-dose pyridoxine (vitamin B6) on stress reduction. Magnesium plays an essential physiological role in the body as an enzymatic cofactor in over 600 biochemical reactions. Low serum magnesium concentrations increase the release of stress-associated and affect their access to the brain.

Potential role of dietary n−3 fatty acids in the prevention of dementia and macular degeneration – Johnson EJ, Schaefer EJ. 2006

Dementia and age-related macular degeneration (AMD) are major causes of disability in the elderly. n−3 Fatty acids, particularly docosahexaenoic acid (DHA), are highly concentrated in brain and retinal tissue and may prevent or delay the progression of dementia and age-related macular degeneration. Low dietary intakes and plasma concentrations have been reported to be associated with dementia, cognitive decline, and age-related macular degeneration risk.