Vitamins and Minerals for Energy, Fatigue and Cognition – Tardy et al. 2020

There is a strong biological and physiological rationale that indicates that the long-known involvement of vitamins and minerals in cellular energy production translates into functional and physiological outcomes in humans, including perceived physical and mental fatigue as well as psychological and cognitive functions.
Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia – Pouteau et al. 2018

Animal and clinical studies suggest complementary effects of magnesium and high-dose pyridoxine (vitamin B6) on stress reduction. Magnesium plays an essential physiological role in the body as an enzymatic cofactor in over 600 biochemical reactions. Low serum magnesium concentrations increase the release of stress-associated and affect their access to the brain.
Docosahexaenoic acid-concentrated fish oil supplementation in subjects with mild cognitive impairment – Lee et al. 2013

Epidemiological studies have suggested a beneficial effect of fish oil supplementation in halting the initial progression of Alzheimer’s disease. A study in 2013 found that the active DHA-rich oil in Active Memory significantly improved memory function including short term and working memory, immediate verbal memory and delayed recall memory.
Potential role of dietary n−3 fatty acids in the prevention of dementia and macular degeneration – Johnson EJ, Schaefer EJ. 2006

Dementia and age-related macular degeneration (AMD) are major causes of disability in the elderly. n−3 Fatty acids, particularly docosahexaenoic acid (DHA), are highly concentrated in brain and retinal tissue and may prevent or delay the progression of dementia and age-related macular degeneration. Low dietary intakes and plasma concentrations have been reported to be associated with dementia, cognitive decline, and age-related macular degeneration risk.
Comparisons between autism spectrum disorders and anxiety disorders – Ooi et al. 2014

Participants showed significant improvements on all subscales of the Social Responsiveness Scale (P<0.01) and the Social and Attention Problems syndrome scales of the Child Behaviour Checklist (P<0.05). Blood fatty acid levels were significantly correlated with changes in the core symptoms of ASD.
The role of polyunsaturated fatty acids in the management of Egyptian children with autism – Meguid et al. 2008

20 of the 30 autistic children had clinically significant improvements in autistic behaviours (CARS)- improved concentration, eye contact, language development and motor skills. Blood DHA and AA increased with treatment from sub-normal levels
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