The effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children – Richardson AJ, Puri BK. 2002

The Beechlawn Study was the first double-blind, placebo controlled trial to be published in a peer reviewed journal. It showed Efalex could reduce a number of ADHD related symptoms including cognitive problems, anxiety and hyperactivity. After 12 weeks mean scores for cognitive problems and general behaviour problems were significantly lower for the group treated with HUFA than for the placebo group

Effects of a high-DHA multi-nutrient supplement and exercise on mobility and cognition in older women – Fairburn, 2019

No treatment effects were observed for the primary outcome, habitual walking speed. Improvements in verbal memory and executive function were seen for all treatments groups v.placebo (all, P < 0·05). Significant improvements in self-reported emotional well-being were seen with multi-nutrient and exercise groups v. placebo (P = 0·03). The results suggest that the high-DHA multi-nutrient supplement produces similar improvements in cognitive function to aerobic exercise, offering the intriguing prospect that supplementation may be able to mitigate some of the effects of low physical activity on cognitive function in the elderly.

A High Omega-3 Fatty Acid Multinutrient Supplement Benefits Cognition and Mobility – Strike SC, Carlisle A, Gibson EL, Dyall SC, 2016

Significant improvements were seen in 2 of the 4 cognitive tests, with shorter mean latencies in a motor screening task (p < .05) & more words remembered (p < .03), and 1 of the 3 primary mobility measures with improved habitual walking speed (p < .05). Compared with the placebo, supplementation also produced significantly higher blood DHA levels (p < .02). This pilot study, showed that Active Memory improved cognition and mobility in able older females at clinically relevant levels, suggesting a potential role in reducing the decline to frailty.

Effect of Omega-3 Multinutrient supplement on memory in older adults – Garcia-Escrivà et al. 2014

Prospective, randomised trial with an unsupplemented control group. This study which was the first one to use Active Memory showed improvements were greater in the Efamol Active Memory treated patients for 5 of the memory tests with the results being significantly greater for delayed prompted text recall. There was no or less deterioration in the Efamol Active Memory treated patients for 5 of the EQ 5D tests with the results for anxiety and depression being significantly less.

Efamol EPO for Mastalgia Treatment – Adni, L. 2021

The results show that EPO was a good as topical NSAIDs, Danazol, and Vitamin E for the treatment of Breast pain. EPO does not increase adverse events such as nausea, abdominal bloating and weight gain compared to placebo or other treatments.

Efamol EPO for Healthy Skin – Muggli 2005

There was a statistically significant improvement in skin moisture, moisture loss, firmness, elasticity, fatigue and smoothness. There was no improvement in any of these parameters following treatment with placebo.

Efamol EPO for Atopic Eczema – Morse & Clough 2006

This study showed that Efamol EPO is a safe and effective remedy for symptomatic relief of atopic eczema with simultaneous benefits on itch, crusting, oedema and redness that become apparent between 4 and 8 weeks after treatment is initiated.

Efamol EPO for Atopic Eczema – Morse & Clough 1989

Significant benefits from EPO as an adjunct to existing treatments, including a 22 % improvement in symptoms in the global assessment. In particular, there was a 25 % improvement in the symptom of itch. Importantly EPO has none of the side effects associated with antihistamines often given for itchy skin.